The process for Updating the Cost/Price of a SKU/Product will vary depending on if your products have variations or not.
If the product does not have variations, updating the Cost/Price on the SKU will update the Product as well.
If the product does have variations, updating the Cost/Price on the SKU will not update the Product. You can update the Price on the Product if you would like to change what is shown on the B2B website prior to the user selecing a variation option.
In both scenarios, updating the Product Cost/Price will not update the SKU